Animal StudyPubMedIndian Journal of Pharmacology
Hexarelin Promotes Survival of Retinal Ganglion Cells After Optic Nerve Injury
Chow KBS
Summary
Hexarelin, a growth hormone secretagogue, promoted survival of retinal ganglion cells after optic nerve transection, suggesting neuroprotective applications.
Clinical Significance
Extends the known neuroprotective properties of GH secretagogues to retinal protection, potentially relevant to glaucoma and optic neuropathy.
Key Findings
- Hexarelin increased retinal ganglion cell survival post-injury
- Neuroprotective effect independent of GH release
- Mechanism involves anti-apoptotic signaling
- Potential application in optic neuropathy and glaucoma
Source
Verwandte Forschung
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