Kisspeptin
Kisspeptin dosing, reproductive hormone mechanism, side effects, and fertility applications. GnRH regulation reference.
Hormone OptimizationSubcutaneous injection, intravenous1-10mcg/kg
Overview
Kisspeptin is a neuropeptide encoded by the KISS1 gene that acts as the master regulator of reproductive function by activating GnRH neurons.
Mechanism of Action
- GnRH neuron activation — Primary upstream trigger for GnRH release
- LH/FSH secretion — Stimulates gonadotropin release
- Reproductive axis regulation — Central to puberty and fertility
- Metabolic sensing — Links energy status to reproductive function
Dosing
Research dosing: 1-10mcg/kg for fertility and reproductive hormone studies.
Last updated: 2026-03-27