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Gonadorelin

Gonadorelin dosing, mechanism of action, side effects, and clinical evidence. Complete reference for healthcare professionals.

Hormone OptimizationSubcutaneous injection100-200mcg twice weekly

Overview

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH) used to stimulate LH and FSH release from the pituitary.

Mechanism of Action

  • GnRH receptor agonism — Stimulates anterior pituitary gonadotrophs
  • LH/FSH release — Pulsatile administration maintains gonadotropin production
  • Testosterone support — Used in place of HCG for testicular stimulation

Dosing

100-200mcg subcutaneously twice weekly to mimic pulsatile GnRH release and maintain testicular function.

Last updated: 2026-03-27