Melanotan II
Melanotan II dosing, side effects, tanning benefits, and melanocortin mechanism of action. Complete clinical reference.
Sexual HealthSubcutaneous injection250-500mcg as needed
Overview
Melanotan II is a synthetic non-selective melanocortin receptor agonist with effects on pigmentation, sexual function, and appetite.
Mechanism of Action
- MC1R agonism — Stimulates melanin production
- MC4R agonism — Affects sexual arousal and appetite
- Non-selective — Acts on multiple melanocortin receptor subtypes
Dosing
250-500mcg subcutaneously. Often used in loading protocols with maintenance dosing.
Safety
Not FDA-approved. Reports of mole changes, nausea, and priapism. Use requires medical supervision.
Last updated: 2026-03-27