AOD-9604
AOD-9604 dosing, fat loss mechanism, side effects, and clinical evidence. GH fragment 177-191 weight loss reference.
Weight LossSubcutaneous injection (oral formulation also investigated)300mcg daily
Overview
AOD-9604 is a modified fragment of human growth hormone (hGH fragment 177-191) studied for its fat-reducing properties without the diabetogenic or growth-promoting effects of full GH.
Mechanism of Action
- Lipolysis stimulation — Enhances fat breakdown in adipose tissue
- Lipogenesis inhibition — Blocks formation of new fatty acids
- No IGF-1 elevation — Does not stimulate growth or insulin resistance
- Cartilage repair — Some evidence of chondroprotective effects
Dosing Protocols
| Protocol | Dose | Frequency | Route | |----------|------|-----------|-------| | Standard | 300mcg | Once daily | Subcutaneous | | Loading | 500mcg | Once daily (4 weeks) | Subcutaneous |
Safety Profile
Generally well tolerated. No significant adverse effects reported in clinical trials. Does not affect blood glucose or IGF-1 levels.
Last updated: 2026-03-27