GLP-1 Drugs, Gastrointestinal Function and Critical Illness
Nadkarni A, Deane AM, Plummer MP
Summary
This review addresses the peri-operative and ICU management of patients on long-acting GLP-1 therapy, concluding that pulmonary aspiration risk is low and not clearly elevated peri-operatively. The authors recommend gastric ultrasound and prokinetic therapy as management tools, and note that GLP-1 therapy does not clearly increase risk of small bowel obstruction or acute pancreatitis.
Clinical Significance
Directly addresses the growing clinical dilemma of managing GLP-1 RA patients in peri-operative and critical care settings. Provides evidence-based guidance for the increasing number of anesthesiologists and intensivists encountering patients on semaglutide and tirzepatide.
Súvisiaci výskum
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