KPV
KPV dosing, mechanism of action, side effects, and clinical evidence. Complete reference for healthcare professionals.
RegenerativeSubcutaneous injection, oral, topical200-500mcg, 1-2x daily
Overview
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH, retaining anti-inflammatory properties without pigmentation effects.
Mechanism of Action
- NF-κB inhibition — Blocks inflammatory signaling pathways
- Gut healing — Reduces intestinal inflammation and promotes mucosal repair
- No pigmentation — Unlike full alpha-MSH, does not stimulate melanocytes
- Wound healing — Accelerates tissue repair
Dosing
200-500mcg subcutaneously or orally, 1-2 times daily. Topical for skin inflammation.
Last updated: 2026-03-27