DSIP
DSIP dosing, mechanism of action, side effects, and clinical evidence. Complete reference for healthcare professionals.
NootropicSubcutaneous injection, intranasal100-250mcg before bed
Overview
DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide that promotes delta-wave sleep and modulates stress responses.
Mechanism of Action
- Sleep promotion — Enhances slow-wave (delta) sleep
- Stress modulation — Normalizes cortisol and blood pressure under stress
- Pain modulation — Analgesic effects through endorphin pathways
- Antioxidant — Reduces oxidative stress markers
Dosing
100-250mcg injected subcutaneously 30-60 minutes before bed. Intranasal also used.
Last updated: 2026-03-27