IGF-1 LR3
IGF-1 LR3 dosing, mechanism of action, side effects, and muscle growth benefits. Long-acting IGF-1 analog reference.
Growth HormoneSubcutaneous injection, intramuscular20-50mcg daily
Overview
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified form of IGF-1 with extended half-life (~20-30 hours vs ~10 minutes for native IGF-1).
Mechanism of Action
- Anabolic signaling — Promotes protein synthesis and muscle growth
- Fat metabolism — Enhances lipolysis
- Recovery — Accelerates tissue repair post-exercise
- Receptor binding — Reduced affinity for IGFBPs extends activity
Dosing
20-50mcg subcutaneously daily, typically post-workout. Cycle 4-6 weeks on, 4 weeks off.
Safety
Not FDA-approved. Can cause hypoglycemia. Should be used under medical supervision.
Last updated: 2026-03-27