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Peptides for weight loss

GLP-1 receptor agonists like semaglutide and tirzepatide have transformed weight management. Explore the research, compare options, and understand what to expect.

Key Peptides

Latest Articles

Review

Best Peptides for Visceral Fat Reduction: What the Research Shows

Visceral fat is the most metabolically dangerous fat in your body. These peptides have demonstrated …

Informational

GLP-1 Weight Loss Timeline: What to Expect Month by Month

Starting a GLP-1 receptor agonist for weight loss? Here's a month-by-month breakdown of what clinica…

Informational

How Peptides Control Appetite: The Science of Hunger Hormones

From GLP-1 to ghrelin, peptide hormones are the master regulators of hunger and satiety. This guide …

Guide

Peptide Weight Loss Programs: What They Actually Cost in 2026

From compounding pharmacies to branded medications and telehealth programs, the cost of peptide-base…

Review

Tirzepatide vs Retatrutide: Comparing Next-Generation Weight Loss Peptides

Tirzepatide is the current weight loss champion, but retatrutide — a triple-receptor agonist — is co…

Guide

Weight Loss Peptide Stack: Building an Evidence-Based Fat Loss Protocol

Combining peptides with complementary mechanisms can enhance fat loss, preserve muscle, and optimize…

Clinical

GLP-1 Receptor Agonists: A Comprehensive Comparison for Prescribers

Trying to figure out which GLP-1 medication is right for you? Here's a plain-English breakdown of th…

Clinical

GLP-1 and Exercise: How to Maximize Weight Loss with Physical Activity

Taking a GLP-1 medication? Here's why exercise isn't optional — and how to protect your muscles whil…

Research

Post hoc analysis of randomized clinical trialPubMed

Cardiorenal Outcomes With Tirzepatide Compared With Dulaglutide in Patients With Diabetes and Cardiovascular Disease: SURPASS-CVOT

In a post hoc analysis of the landmark SURPASS-CVOT trial (n=13,165), tirzepatide demonstrated a 16%…

TirzepatideDulaglutide
Phase 3b randomized clinical trialPubMed

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: TOGETHER-PsA Trial

In the TOGETHER-PsA trial (n=271), combining tirzepatide with ixekizumab achieved ACR50 + ≥10% weigh…

Tirzepatide
Model-Informed Drug Development (MIDD) / Post-hoc AnalysisPubMed

Efficacy, Safety and Pharmacokinetics of Semaglutide 1.7 mg for Obesity Treatment in Adolescents: A Model-Informed Drug Development Approach

This Novo Nordisk study used model-informed drug development to evaluate whether semaglutide 1.7 mg …

Semaglutide
Systematic Review and Meta-AnalysisPubMed

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Depression: A Systematic Review and Meta-Analysis

This comprehensive meta-analysis evaluated the association between GLP-1 receptor agonist use and de…

GLP-1 receptor agonistssemaglutideliraglutide
Retrospective cohort study (n=293)PubMed

Real-World Weight-Loss Outcomes in Weight-Reduced Patients Treated With Tirzepatide

This real-world study of 293 patients found that tirzepatide produced 10.3% total body weight loss i…

TirzepatideSemaglutide
Systematic review and meta-analysisPubMed

Glucagon-like Peptide-1 Receptor Agonists and Risk of Depression: A Systematic Review and Meta-Analysis

This comprehensive meta-analysis examined the relationship between GLP-1 receptor agonist use and de…

GLP-1 receptor agonistsSemaglutideLiraglutide

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