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Centre Thématique

Peptides pour la perte de poids

Les agonistes des récepteurs GLP-1 comme le sémaglutide et le tirzépatide ont transformé la gestion du poids. Explorez la recherche, comparez les options et comprenez à quoi vous attendre.

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Post hoc analysis of randomized clinical trialPubMed

Cardiorenal Outcomes With Tirzepatide Compared With Dulaglutide in Patients With Diabetes and Cardiovascular Disease: SURPASS-CVOT

In a post hoc analysis of the landmark SURPASS-CVOT trial (n=13,165), tirzepatide demonstrated a 16%…

TirzepatideDulaglutide
Phase 3b randomized clinical trialPubMed

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: TOGETHER-PsA Trial

In the TOGETHER-PsA trial (n=271), combining tirzepatide with ixekizumab achieved ACR50 + ≥10% weigh…

Tirzepatide
Model-Informed Drug Development (MIDD) / Post-hoc AnalysisPubMed

Efficacy, Safety and Pharmacokinetics of Semaglutide 1.7 mg for Obesity Treatment in Adolescents: A Model-Informed Drug Development Approach

This Novo Nordisk study used model-informed drug development to evaluate whether semaglutide 1.7 mg …

Semaglutide
Systematic Review and Meta-AnalysisPubMed

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Depression: A Systematic Review and Meta-Analysis

This comprehensive meta-analysis evaluated the association between GLP-1 receptor agonist use and de…

GLP-1 receptor agonistssemaglutideliraglutide
Retrospective cohort study (n=293)PubMed

Real-World Weight-Loss Outcomes in Weight-Reduced Patients Treated With Tirzepatide

This real-world study of 293 patients found that tirzepatide produced 10.3% total body weight loss i…

TirzepatideSemaglutide
Systematic review and meta-analysisPubMed

Glucagon-like Peptide-1 Receptor Agonists and Risk of Depression: A Systematic Review and Meta-Analysis

This comprehensive meta-analysis examined the relationship between GLP-1 receptor agonist use and de…

GLP-1 receptor agonistsSemaglutideLiraglutide

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