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Epithalon

Hormone Optimization
Hormone OptimizationEvidence-based

Epithalon

Epithalon dosing, telomerase activation, side effects, and anti-aging benefits. Synthetic tetrapeptide reference guide.

💉 Subcutaneous injection (SC, IM)📊 5-10mg daily for 10-20 day cycles📋 Preclinical

Last updated: 2026-03-27

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Category

Hormone Optimization

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Route

Subcutaneous injection (SC, IM)

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Dosing

5-10mg daily for 10-20 day cycles

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Evidence

Preclinical

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Availability

available

Overview

Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural epithalamin produced by the pineal gland, studied for telomerase activation and potential anti-aging properties.

Mechanism of Action

  • Telomerase activation — Stimulates telomerase activity in human cells
  • Melatonin regulation — Normalizes melatonin secretion from the pineal gland
  • Cellular senescence — May delay cellular aging processes
  • Antioxidant effects — Reduces oxidative stress markers

Dosing Protocols

ProtocolDoseDurationRoute
Standard5-10mg daily10-20 daysSubcutaneous
Cycling10mg daily10 days on, 20 days offSubcutaneous

Safety Profile

Limited human data. Used in Russian clinical practice. Generally well tolerated with few reported side effects.

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